A broad range of tools is required to meet reliability goals for robust electronic systems. Designing robust electronic systems requires a multi-step approach with emphasis on reliability simulations. High-performance integrated circuits (ICs) are the workhorses of today’s electronics industry. Designers must pay special attention to verifying these ICs for several operating and stress conditions to deliver a robust electronic system. Simulations such as supply noise coupling, thermal impact on electromigration (EM), electromagnetic interference (EMI) and electrostatic discharge (ESD) are key aspects of IC reliability verification.